Cervical weakness and infection have long been regarded as major causes of preterm birth. Cervical cerclage has been used extensively to reduce the risk of preterm birth arising as a result of cervical weakness, but increasing evidence suggests that the cervix plays more than just a mechanical role. Immunological function of the cervix and mucus plug is thought to be important in minimising the ascent of microbes, which can lead to chorioamnionitis and rupture of the amniotic membranes.

If you need further information, please do not hesitate to contact us with your questions:

Professor Niels Jørgen Secher
Department of Obstetrics and Gynecology
Copenhagen University Hospital in Hvidovre
Telephone: + 45 36 32 26 22
E-mail: njsecher@dadlnet.dk

C. D. McCormack, BSc, MbChB, FCOG (SA)
Women’s and Children’s Hospital,
72 King William Road
Adelaide
South Australia 5006
E-mail: deemccormack@hotmail.com